分子科学公共实验平台依托西湖大学理学院筹建，自2020年7月起作为校级平台运行，在学校的大力支持下，逐步建设以光谱、色质谱、磁共振波谱以及in-house同步辐射等为技术核心的原位、高分辨分子科学表征体系，服务功能分子合成、绿色催化、能源材料、环境生态及化学生物等前沿科研方向，为西湖大学三大学院相关学科的蓬勃发展、PI实验室的科研推进、学生实验素养及数据解析技能的不断提高而全力服务。
平台秉承“技术驱动创新”的理念，以新工具促进新科学的发展，为全校师生提供最新一代原子/分子谱学表征的7*24小时自主、开放仪器使用环境，并积极开展新方法学、新技术的开发实践及其在用户实际科研体系上的应用。平台主要由三个专业检测实验室组成：（1）磁共振实验室旨在为分子结构、分子间相互作用和分子动力学信息的获取和解析提供一流的设备与技术支撑，其中核磁共振和电子顺磁共振对核自旋和超精细相互作用的精确操控，使其成为功能分子合成、物理化学、材料科学、分子医学和结构生物学等研究领域的高分辨表征工具。（2）色质谱实验室面向化学、材料、环境、食品、生物等领域，以小分子、聚合物为研究对象，依靠高灵敏度、高分辨率的各类色质谱技术进行化合物纯化、制备及定性、定量分析，并开展对于合成分子，尤其是手性异构体分子的色质谱方法研究。（3）光谱及化学反应优化实验室提供从X射线、近紫外、可见光到中红外区的稳态和瞬态光谱的先进原位表征和微区表征，用于能级结构、配位环境、成分价态、分子几何以及化学键性质的研究，实现从皮秒到秒的分子反应动力学监测。各实验室均配有经验丰富的资深技术人员，为仪器维护、人员培训保驾护航，为设备研制、功能开发锐意创新；并瞄准分子科学领域关键的表征技术难题，开展基础性、前瞻性、多学科多技术交叉的分析测试新方法、新工具的研发。
与此同时，平台面向社会开放共享，技术服务项目包含但不仅限于有机/无机成分与结构分析，药物及聚合物定性/定量分析，材料结构及功能分析，多肽及生物大分子构象/动力学和稳定性分析，临床标志物的代谢组学分析，以及水质检测、食品检测、环境污染物检测等，积极为地方和国家的科研和经济建设提供助力。
The Instrumentation and Service Center for Molecular Sciences (ISCMS) is a shared-use core facility at Westlake University. She was initiated by the School of Science with a very clear vision: To provide a collaborative multi-disciplinary research environment to support of the creation and evolution of world-class molecular sciences and technical expertise, for the Westlake research community as well as the larger community of external researchers both from academia and industry.
ISMCS is mainly composed of three professional analytical laboratories:
(1) Magnetic Resonance Lab aims to provide advanced methodologies and facilities for in-situ and high-resolution analysis of molecular structures, interactions and dynamics. The manipulation of nuclear spins and hyperfine interactions by NMR and EPR makes it a comprehensive characterization platform for functional molecule synthesis, physical chemistry, materials science, molecular medicine and structural biology researches.
(2) Chromatography and Mass Spectroscopy Lab focuses on qualitative analysis, quantitative analysis and compound purification for small molecules and polymers in chemistry-, material-, environment- and food-related areas via various chromatography and mass spectrometry techniques. We are dedicated to developing the chromatographic and/or mass spectrometric methods, especially for isomer analysis.
(3) Spectroscopy and Chemical Reaction Optimization Laboratory provides state-of-the-art steady-state / transient-state and micro-area / in-situ spectroscopic characterizations. The wavelength range spans from X-ray absorption, near ultraviolet, visible to mid-infrared, and typical applications include, but not limited to, investigations of energy level structure, molecular geometry, chemical bond properties, and reaction kinetics monitoring from picosecond to second time intervals.
The focus of our technical team at ISCMS has been not only to serve a broad, diverse, international set of researchers who are focused on pioneering scientific innovations, but also to develop specialized methodologies, protocols, instrumentation, and expertise to help simulate, characterize, and analyze novel molecules, materials, and systems going beyond conventional approaches .
